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HEXIM2 Antibody - N-terminal region: Biotin (ARP41121_P050-Biotin)

Product Specifications

Gene Name

Hexamethylene bis-acetamide inducible 2

Gene Aliases

L3

Gene ID

124790

Swiss Prot

Q96MH2

Accession Number

NP_653209

Host

Rabbit

Reactivity

Human, Rat, Dog, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HEXIM2

Target

HEXIM2 belongs to the HEXIM family. It is transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor.In cooperation with 7SK snRNA, HEXIM2 sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

Partner Proteins

TCF12; CCDC36; HEXIM2; PRDM14; RNPS1; TADA3; SPRY2; SPRY1; PIN1; PIM1; MEOX2; GATA1; CDK9; RN7SK; HEXIM1; TERF2; TERF1; MEPCE; CCNT1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Dog: 93%; Horse: 79%; Human: 100%; Pig: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

Shipping Conditions

Wet Ice

Protein Length

286

NCBI Gene Symbol

HEXIM2

Protein Name

Protein HEXIM2

Nucleotide Accession Number

NM_144608

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