RAVER1 Antibody - N-terminal region : Biotin (ARP41099_T100-Biotin)
Selected Variant
ARP41099_T100-Biotin
Size: 100 µL
Product Specifications
Gene Name
Ribonucleoprotein, PTB-binding 1
Gene ID
125950
Swiss Prot
Q8IY67
Accession Number
NP_597709
Host
Rabbit
Reactivity
Human, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human RAVER1
Target
RAVER1 contains 3 RRM (RNA recognition motif) domains. It cooperates with PTBP1 to modulate regulated alternative splicing events and promotes exon skipping. It cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
Partner Proteins
FUS; NEDD1; CEP76; CEP72; HAUS2; CEP250; AURKB; TUBG1; TP53; PPP2R1A; LGALS3BP; CDKN1A; CDC20; AIRE; STAU1; UBC; RPA3; RPA2; RPA1; WHSC1; VCAM1; FN1; MCAT; DYNLT1; SDHA; PHKB; ABCC1; AK2; ELAVL1; SUMO2; Cnot3; TERF2; PTBP1; VCL; ACTN1; ACTN2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 79%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Rabbit: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
67kDa
References & Citations
Beausoleil, S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135
Shipping Conditions
Wet Ice
Protein Length
606
NCBI Gene Symbol
RAVER1
NCBI GB Accession Number
RAVER1
Host or Source
Rabbit
Protein Name
Ribonucleoprotein PTB-binding 1
Nucleotide Accession Number
NM_133452
Peptide Sequence
VTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFR
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