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SRSF10 Antibody - C-terminal region : HRP (ARP41083_P050-HRP)

Selected Variant

ARP41083_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Serine and arginine rich splicing factor 10

Gene Aliases

NSSR, TASR, SRp38, TASR1, TASR2, FUSIP1, FUSIP2, SFRS13, SRrp40, SFRS13A, PPP1R149

Gene ID

10772

Swiss Prot

O75494

Accession Number

NP_473357

Host

Rabbit

Reactivity

Human, Mouse, Rat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human FUSIP1

Target

This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants.

Partner Proteins

STAU1; WWOX; SUZ12; EED; RNF2; EZH2; HECW2; TRA2B; SRSF4; SRSF1; CSNK2A1; EIF4A3; MAGOH; PAXIP1; BARD1; SAP18; VTN; TCOF1; SRSF6; S100A9; PRKDC; NHP2L1; NFIA; SEPT2; MSH2; IK; EPRS; DHX15; BCAS2; TRIM55; THOC6; ZNF687; SMU1; TRMT112; TRA2A; PHGDH; NCSTN

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

References & Citations

Shi, Y. (2007) Mol. Cell 28 (1), 79-90

Shipping Conditions

Wet Ice

Protein Length

262

NCBI Gene Symbol

SRSF10

NCBI GB Accession Number

SRSF10

Host or Source

Rabbit

Protein Name

Serine/arginine-rich splicing factor 10

Nucleotide Accession Number

NM_054016

Peptide Sequence

KSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEK

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