SRSF10 Antibody - C-terminal region : FITC (ARP41083_P050-FITC)
Product Specifications
Gene Name
Serine and arginine rich splicing factor 10
Gene Aliases
NSSR, TASR, SRp38, TASR1, TASR2, FUSIP1, FUSIP2, SFRS13, SRrp40, SFRS13A, PPP1R149
Gene ID
10772
Swiss Prot
O75494
Accession Number
NP_473357
Host
Rabbit
Reactivity
Human, Mouse, Rat, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human FUSIP1
Target
This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants.
Partner Proteins
STAU1; WWOX; SUZ12; EED; RNF2; EZH2; HECW2; TRA2B; SRSF4; SRSF1; CSNK2A1; EIF4A3; MAGOH; PAXIP1; BARD1; SAP18; VTN; TCOF1; SRSF6; S100A9; PRKDC; NHP2L1; NFIA; SEPT2; MSH2; IK; EPRS; DHX15; BCAS2; TRIM55; THOC6; ZNF687; SMU1; TRMT112; TRA2A; PHGDH; NCSTN
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
31kDa
References & Citations
Shi, Y. (2007) Mol. Cell 28 (1), 79-90
Shipping Conditions
Wet Ice
Protein Length
262
NCBI Gene Symbol
SRSF10
NCBI GB Accession Number
SRSF10
Host or Source
Rabbit
Protein Name
Serine/arginine-rich splicing factor 10
Nucleotide Accession Number
NM_054016
Peptide Sequence
KSNSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEK
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