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PNPT1 Antibody - middle region : Biotin (ARP41066_P050-Biotin)

Product Specifications

Gene Name

Polyribonucleotide nucleotidyltransferase 1

Gene Aliases

OLD35, DFNB70, PNPASE, old-35, COXPD13

Gene ID

87178

Swiss Prot

Q8TCS8

Accession Number

NP_149100

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PNPT1

Target

PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation.PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation (Raijmakers et al., 2002 [PubMed 12419256]) .[supplied by OMIM]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

GRSF1; UBC; GATC; DPY30; NUP107; NUP153; NCAPD2; PDLIM1; NUP214; RANGAP1; PTBP1; PRKCSH; NCL; HSPB1; SIRT7; ICT1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

86kDa

References & Citations

Slomovic, S. (2008) RNA 14 (2), 310-323

Shipping Conditions

Wet Ice

Protein Length

783

NCBI Gene Symbol

PNPT1

NCBI GB Accession Number

PNPT1

Host or Source

Rabbit

Protein Name

Polyribonucleotide nucleotidyltransferase 1, mitochondrial

Nucleotide Accession Number

NM_033109

Peptide Sequence

CGGSLALMDSGVPISSAVAGVAIGLVTKTDPEKGEIEDYRLLTDILGIED

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