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BOLL Antibody - N-terminal region : Biotin (ARP41065_P050-Biotin)

Product Specifications

Gene Name

Bol, boule-like (Drosophila)

Gene Aliases

BOULE

Gene ID

66037

Swiss Prot

Q8N9W6

Accession Number

NP_149019

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human BOLL

Target

This gene belongs to the DAZ gene family required for germ cell development. BOLL is an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like) . Loss of this gene function results in the absence of sperm in semen (azoospermia) . Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like) . Loss of this gene function results in the absence of sperm in semen (azoospermia) . Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Partner Proteins

ZNF385C; HNRNPLL; C1orf94; RBFOX2; RBPMS; TFG; SERF2; NPBWR2; DAZ1; DAZ4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Goat: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

31kDa

References & Citations

Kostova, E., (2007) Mol. Hum. Reprod. 13 (2), 85-93

Shipping Conditions

Wet Ice

Protein Length

283

NCBI Gene Symbol

BOLL

NCBI GB Accession Number

BOLL

Host or Source

Rabbit

Protein Name

Protein boule-like

Nucleotide Accession Number

NM_033030

Peptide Sequence

GGIDFKTNESDLRKFFSQYGSVKEVKIVNDRAGVSKGYGFVTFETQEDAQ

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