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NXF5 Antibody - middle region : FITC (ARP41062_T100-FITC)

Selected Variant

ARP41062_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Nuclear RNA export factor 5

Gene ID

55998

Swiss Prot

Q9H1B4

Accession Number

NP_116564

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NXF5

Target

NXF5 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2) -like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2) -like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. Five transcript variants that encode different isoforms have been found for this gene.

Partner Proteins

NXF1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Dog: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Frints, S.G., (2003) Am. J. Med. Genet. A 119 (3), 367-374

Shipping Conditions

Wet Ice

Protein Length

397

NCBI Gene Symbol

NXF5

NCBI GB Accession Number

NXF5

Host or Source

Rabbit

Protein Name

Nuclear RNA export factor 5

Nucleotide Accession Number

NM_032946

Peptide Sequence

ITERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWE

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