NXF5 Antibody - middle region : FITC (ARP41062_T100-FITC)
Selected Variant
ARP41062_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
Nuclear RNA export factor 5
Gene ID
55998
Swiss Prot
Q9H1B4
Accession Number
NP_116564
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NXF5
Target
NXF5 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2) -like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2) -like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. Five transcript variants that encode different isoforms have been found for this gene.
Partner Proteins
NXF1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Dog: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
44kDa
References & Citations
Frints, S.G., (2003) Am. J. Med. Genet. A 119 (3), 367-374
Shipping Conditions
Wet Ice
Protein Length
397
NCBI Gene Symbol
NXF5
NCBI GB Accession Number
NXF5
Host or Source
Rabbit
Protein Name
Nuclear RNA export factor 5
Nucleotide Accession Number
NM_032946
Peptide Sequence
ITERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWE
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