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C14ORF156 Antibody - N-terminal region : Biotin (ARP41033_P050-Biotin)

Selected Variant

ARP41033_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

SRA stem-loop interacting RNA binding protein

Gene Aliases

DC50, PD04872, C14orf156

Gene ID

81892

Swiss Prot

Q9GZT3

Accession Number

NP_112487

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human C14ORF156

Target

As a RNA-binding protein, C14orf156 acts as a nuclear receptor corepressor. It probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. C14orf156 binds the STR7 loop of SRA RNA. It is also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.

Partner Proteins

KRT40; CCDC102B; MTUS2; PNMA1; HAUS2; VCP; UBC; MDM2; ASB5; ADRB2; vpu; CSNK2A1; SCAMP3; RBM8A; MRRF; SUGP1; SBDS; U2AF2; DSTN; SF3B4; HNRNPR; PPIF; SNRPC; SNRNP70; RPL38; RFX5; PIN4; ILF3; HNRNPA2B1; ELAVL1; EIF4G2; PQBP1; ICT1; SLX1B; BABAM1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

SLIRP is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Horse: 86%; Human: 100%; Pig: 79%; Rabbit: 86%; Sheep: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

12kDa

References & Citations

Xu, X., Unpublished (2000)

Shipping Conditions

Wet Ice

Protein Length

109

NCBI Gene Symbol

SLIRP

NCBI GB Accession Number

SLIRP

Host or Source

Rabbit

Protein Name

SRA stem-loop-interacting RNA-binding protein, mitochondrial

Nucleotide Accession Number

NM_031210

Peptide Sequence

PFDKETGFHRGLGWVQFSSEEGLRNALQQENHIIDGVKVQVHTRRPKLPQ

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