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DDX17 Antibody - N-terminal region : HRP (ARP41029_T100-HRP)

Selected Variant

ARP41029_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

DEAD (Asp-Glu-Ala-Asp) box helicase 17

Gene Aliases

P72, RH70

Gene ID

10521

Swiss Prot

Q92841

Accession Number

EAW60248

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DDX17

Target

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The DEAD box protein is an ATPase activated by a variety of RNA species but not by dsDNA. This protein and that encoded by DDX5 gene are more closely related to each other than to any other member of the DEAD box family.

Partner Proteins

BYSL; GRB2; RBM15; CEP250; UBC; SUMO2; SUMO3; SPRTN; STAU1; CDC37; IVNS1ABP; SUMO1; LGR4; MDM2; NEDD8; RPA3; RPA2; RPA1; WWOX; EED; rev; P3H1; LSM1; PRPSAP1; PIN1; DDX5; APBB1; PARK2; FBXO6; TARDBP; WBP11; SF1; UBD; IGSF8; ICAM1; CD81; SF3B4; WHSC1; VCAM1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

DDX17 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

References & Citations

Venter, J.C. (2001) Science 291 (5507), 1304-1351

Shipping Conditions

Wet Ice

Protein Length

547

NCBI Gene Symbol

DDX17

NCBI GB Accession Number

DDX17

Host or Source

Rabbit

Protein Name

Probable ATP-dependent RNA helicase DDX17

Nucleotide Accession Number

NM_001098504

Peptide Sequence

TSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGY

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