DDX17 Antibody - N-terminal region : FITC (ARP41029_T100-FITC)
Product Specifications
Gene Name
DEAD (Asp-Glu-Ala-Asp) box helicase 17
Gene Aliases
P72, RH70
Gene ID
10521
Swiss Prot
Q92841
Accession Number
EAW60248
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human DDX17
Target
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The DEAD box protein is an ATPase activated by a variety of RNA species but not by dsDNA. This protein and that encoded by DDX5 gene are more closely related to each other than to any other member of the DEAD box family.
Partner Proteins
BYSL; GRB2; RBM15; CEP250; UBC; SUMO2; SUMO3; SPRTN; STAU1; CDC37; IVNS1ABP; SUMO1; LGR4; MDM2; NEDD8; RPA3; RPA2; RPA1; WWOX; EED; rev; P3H1; LSM1; PRPSAP1; PIN1; DDX5; APBB1; PARK2; FBXO6; TARDBP; WBP11; SF1; UBD; IGSF8; ICAM1; CD81; SF3B4; WHSC1; VCAM1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
DDX17 is supported by BioGPS gene expression data to be expressed in Jurkat
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
60kDa
References & Citations
Venter, J.C. (2001) Science 291 (5507), 1304-1351
Shipping Conditions
Wet Ice
Protein Length
547
NCBI Gene Symbol
DDX17
NCBI GB Accession Number
DDX17
Host or Source
Rabbit
Protein Name
Probable ATP-dependent RNA helicase DDX17
Nucleotide Accession Number
NM_001098504
Peptide Sequence
TSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGY
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