UPF3A Antibody - middle region : HRP (ARP41000_P050-HRP)
Product Specifications
Gene Name
UPF3 regulator of nonsense transcripts homolog A (yeast)
Gene Aliases
UPF3, HUPF3A, RENT3A
Gene ID
65110
Swiss Prot
Q9H1J1
Accession Number
NP_075387
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human UPF3A
Target
UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon j
Partner Proteins
HTT; SMG1; HBB; APP; RNPS1; NXF1; SRRM1; TOPORS; PIGT; ALYREF; IFITM2; RBM8A; GSK3B; UPF1; UPF2; DCP2; UPF3B; EXOSC4; XRN1; EXOSC2; EXOSC10; PARN
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
55kDa
References & Citations
Singh, G., (2007) Mol. Cell 27 (5), 780-792
Shipping Conditions
Wet Ice
Protein Length
476
NCBI Gene Symbol
UPF3A
NCBI GB Accession Number
UPF3A
Host or Source
Rabbit
Protein Name
Regulator of nonsense transcripts 3A
Nucleotide Accession Number
NM_023011
Peptide Sequence
QRYHVDDGRRHRAHHEPERLSRRSEDEQRWGKGPGQDRGKKGSQDSGAPG
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