UPF3A Antibody - middle region : Biotin (ARP41000_P050-Biotin)

Product Specifications

Gene Name

UPF3 regulator of nonsense transcripts homolog A (yeast)

Gene Aliases

UPF3, HUPF3A, RENT3A

Gene ID

65110

Swiss Prot

Q9H1J1

Accession Number

NP_075387

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human UPF3A

Target

UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon j

Partner Proteins

HTT; SMG1; HBB; APP; RNPS1; NXF1; SRRM1; TOPORS; PIGT; ALYREF; IFITM2; RBM8A; GSK3B; UPF1; UPF2; DCP2; UPF3B; EXOSC4; XRN1; EXOSC2; EXOSC10; PARN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.