DGCR8 Antibody - N-terminal region : Biotin (ARP40984_P050-Biotin)

Product Specifications

Gene Name

DiGeorge syndrome critical region gene 8

Gene Aliases

Gy1, pasha, DGCRK6, C22orf12

Gene ID

54487

Swiss Prot

Q8WYQ5

Accession Number

NP_073557

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DGCR8

Target

DGCR8 contains 2 DRBM (double-stranded RNA-binding) domains and 1 WW domain. It may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies.

Partner Proteins

MEOX2; PYCRL; DROSHA; RAE1; MAPK1; PRMT1; ERH; CDKN2A; BMI1; SRPK2; SRPK1; CDT1; NAT10; PLEK2; RPRD2; MAPRE2; PRPF4; FLII; APP; CUL3; DDX17; HNRNPR; NCL; ILF3; HSPA8; HSPA5; HNRNPU; HNRNPH1; FUS; DHX9; DDX5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 85%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.