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TNRC6A Antibody - N-terminal region : Biotin (ARP40956_P050-Biotin)

Product Specifications

Gene Name

Trinucleotide repeat containing 6A

Gene Aliases

GW1, FAME6, GW182, TNRC6, CAGH26

Gene ID

27327

Swiss Prot

Q8NDV7

Accession Number

NP_055309

Host

Rabbit

Reactivity

Human, Mouse, Dog, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TNRC6A

Target

TNRC6A is a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

TRIP13; CEP250; TRIM65; AGO3; AGO2; AGO1; UBC; SAV1; AGO4; CUL3; UBR5; PABPC1; WNK1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 93%; Horse: 100%; Human: 100%; Mouse: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

210kDa

References & Citations

Eulalio, A., (2008) Nat. Struct. Mol. Biol. 15 (4), 346-353

Shipping Conditions

Wet Ice

Protein Length

1962

NCBI Gene Symbol

TNRC6A

NCBI GB Accession Number

TNRC6A

Host or Source

Rabbit

Protein Name

Trinucleotide repeat-containing gene 6A protein

Nucleotide Accession Number

NM_014494

Peptide Sequence

RELEAKATKDVERNLSRDLVQEEEQLMEEKKKKKDDKKKKEAAQKKATEQ

Frequently Asked Questions

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