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EXOSC4 Antibody - N-terminal region : HRP (ARP40935_T100-HRP)

Product Specifications

Gene Name

Exosome component 4

Gene Aliases

SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, hRrp41p

Gene ID

54512

Swiss Prot

Q9NPD3

Accession Number

NP_061910

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC4

Target

EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.

Partner Proteins

EED; TOM1; NMI; H1FX; HIST1H1E; TSEN15; GADD45GIP1; FAHD1; SMPD4; LRRC8D; EXOSC1; EXOSC3; MPZL1; SKIV2L; EXOSC10; EXOSC9; NEK1; HNRNPD; DXO; AICDA; UBC; ESR2; EXOSC5; DDX47; EXOSC2; EXOSC7; EXOSC8; PSIP1; EXOSC6; DIS3L; EXOSC4; SKIV2L2; DIS3; UPF2; MPP6

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

References & Citations

Oh, J.H., (2005) Mamm. Genome 16 (12), 942-954

Shipping Conditions

Wet Ice

Product Datasheet

Anti-EXOSC4 (ARP40935_T100-HRP) antibody

Protein Length

245

NCBI Gene Symbol

EXOSC4

NCBI GB Accession Number

EXOSC4

Host or Source

Rabbit

Protein Name

Exosome complex component RRP41

Nucleotide Accession Number

NM_019037

Peptide Sequence

SDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHE

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