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EXOSC4 Antibody - N-terminal region : HRP (ARP40935_T100-HRP)

Selected Variant

ARP40935_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Exosome component 4

Gene Aliases

SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, hRrp41p

Gene ID

54512

Swiss Prot

Q9NPD3

Accession Number

NP_061910

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC4

Target

EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.

Partner Proteins

EED; TOM1; NMI; H1FX; HIST1H1E; TSEN15; GADD45GIP1; FAHD1; SMPD4; LRRC8D; EXOSC1; EXOSC3; MPZL1; SKIV2L; EXOSC10; EXOSC9; NEK1; HNRNPD; DXO; AICDA; UBC; ESR2; EXOSC5; DDX47; EXOSC2; EXOSC7; EXOSC8; PSIP1; EXOSC6; DIS3L; EXOSC4; SKIV2L2; DIS3; UPF2; MPP6

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

References & Citations

Oh, J.H., (2005) Mamm. Genome 16 (12), 942-954

Shipping Conditions

Wet Ice

Protein Length

245

NCBI Gene Symbol

EXOSC4

NCBI GB Accession Number

EXOSC4

Host or Source

Rabbit

Protein Name

Exosome complex component RRP41

Nucleotide Accession Number

NM_019037

Peptide Sequence

SDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHE

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