XRN1 Antibody - middle region : Biotin (ARP40931_P050-Biotin)

Product Specifications

Gene Name

5'-3' exoribonuclease 1

Gene Aliases

45170

Gene ID

54464

Swiss Prot

Q8IZH2

Accession Number

NP_061874

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human XRN1

Target

SEP1 (XRN1) localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-67 BX640905.1 1-67 68-5188 AY137776.1 1-5121 5189-5269 BG197321.1 308-388 5270-10092 AC023508.16 31718-36540 c

Partner Proteins

ZFP36; UBC; RPA3; RPA2; RPA1; BMI1; HECW2; HERC2P4; RNF187; B3GALT6; EXOSC6; C1orf85; VWA5B2; MFSD5; PRADC1; ANGPTL6; PLEKHG2; SPATA20; C1GALT1; DCP1A; HEATR1; NDUFA13; EXOSC1; DPP7; RBMX; MTCH2; TMEM50A; CD97; ATP5G2; SNHG1; LINC01541; DCP1B; SRRM2; SKIV

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Dog: 93%; Guinea Pig: 79%; Horse: 90%; Human: 100%; Mouse: 86%; Pig: 85%; Rabbit: 100%; Rat: 100%; Yeast: 90%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.