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A2BP1 Antibody - N-terminal region : HRP (ARP40921_P050-HRP)

Product Specifications

Gene Name

RNA binding protein, fox-1 homolog (C. elegans) 1

Gene Aliases

2BP1, FOX1, A2BP1, FOX-1, HRNBP1

Gene ID

54715

Swiss Prot

Q9NWB1

Accession Number

NP_061193

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human A2BP1

Target

Ataxin-2 binding protein 1 (A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2) . Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.

Partner Proteins

C1orf94; RBPMS; PRR20A; HSFY1; RHOXF2; ALG13; RBFOX1; FAM168A; DAZAP2; MAGED1; BHLHE40; SNRPN; DAB1; CRX; UBC; HSFX1; RBM24; LZTS2; DMRTB1; PCBP4; NOC2L; GCA; RBFOX2; KIFAP3; CELF3; PSMF1; QKI; NUMBL; PRRC2A; ATXN2; ATXN1; HNRNPF; DVL2; ATN1; TNIP1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

Shipping Conditions

Wet Ice

Product Datasheet

Anti-RBFOX1 (ARP40921_P050-HRP) antibody

Protein Length

397

NCBI Gene Symbol

RBFOX1

NCBI GB Accession Number

RBFOX1

Host or Source

Rabbit

Protein Name

RNA binding protein fox-1 homolog 1

Nucleotide Accession Number

NM_018723

Peptide Sequence

SAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRD

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