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ENOX1 Antibody - middle region : Biotin (ARP40886_P050-Biotin)

Product Specifications

Gene Name

Ecto-NOX disulfide-thiol exchanger 1

Gene Aliases

CNOX, PIG38, cCNOX, bA64J21.1

Gene ID

55068

Swiss Prot

Q8TC92

Accession Number

NP_060463

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ENOX1

Target

Electron transport pathways are generally associated with mitochondrial membranes, but non-mitochondrial pathways are also biologically significant. Plasma membrane electron transport pathways are involved in functions as diverse as cellular defense, intracellular redox homeostasis, and control of cell growth and survival. Members of the ecto-NOX family, such as CNOX, or ENOX1, are involved in plasma membrane transport pathways. These enzymes exhibit both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity in series, with each activity cycling every 22 to 26 minutes.Electron transport pathways are generally associated with mitochondrial membranes, but non-mitochondrial pathways are also biologically significant. Plasma membrane electron transport pathways are involved in functions as diverse as cellular defense, intracellular redox homeostasis, and control of cell growth and survival. Members of the ecto-NOX family, such as CNOX, or ENOX1, are involved in plasma membrane transport pathways. These enzymes exhibit both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity in series, with each activity cycling every 22 to 26 minutes (Scarlett et al., 2005 [PubMed 15882838]) .[supplied by OMIM].

Partner Proteins

TRIM43; ZMYND19; GORASP2; ENOX2; SDCBP; BMI1; UBC; LNX1; ZBTB16; EEF1G; NIF3L1; SULT1E1; EIF6

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

73kDa

References & Citations

Oh, J.H., (2005) Mamm. Genome 16 (12), 942-954

Shipping Conditions

Wet Ice

Protein Length

643

NCBI Gene Symbol

ENOX1

NCBI GB Accession Number

ENOX1

Host or Source

Rabbit

Protein Name

Ecto-NOX disulfide-thiol exchanger 1

Nucleotide Accession Number

NM_017993

Peptide Sequence

QQLQFLQQTMQGMQQQLLTIQEELNNKKSELEQAKEEQSHTQALLKVLQE

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