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CPSF2 Antibody - N-terminal region : HRP (ARP40857_P050-HRP)

Product Specifications

Gene Name

Cleavage and polyadenylation specific factor 2, 100kDa

Gene Aliases

CPSF100

Gene ID

53981

Swiss Prot

Q9P2I0

Accession Number

NP_059133

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CPSF2

Target

CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.

Partner Proteins

RBBP6; UBC; WWOX; EZH2; rev; HECW2; CLK2; NPM1; CPSF3; SYMPK; CSTF2; MDC1; ECT2; BARD1; GTF3C6; FIP1L1; WDR33; POLE3; CPSF1; RALBP1; MED17; GTF3C3; SMARCD3; SMARCA4; POLR2A; CUL3; HNRNPA1; ELAVL1; SUMO2; SMARCAD1; CSTF2T; RRAGA; TBP; PSMA3; CLP1; CDC73; R

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

782

NCBI Gene Symbol

CPSF2

NCBI GB Accession Number

CPSF2

Host or Source

Rabbit

Protein Name

Cleavage and polyadenylation specificity factor subunit 2

Nucleotide Accession Number

NM_017437

Peptide Sequence

YAVGKLGLNCAIYATIPVYKMGQMFMYDLYQSRHNTEDFTLFTLDDVDAA

Subunit

2

Frequently Asked Questions

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