CPSF2 Antibody - N-terminal region : Biotin (ARP40857_P050-Biotin)

Product Specifications

Gene Name

Cleavage and polyadenylation specific factor 2, 100kDa

Gene Aliases

CPSF100

Gene ID

53981

Swiss Prot

Q9P2I0

Accession Number

NP_059133

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CPSF2

Target

CPSF2 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. It belongs to the metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily.

Partner Proteins

RBBP6; UBC; WWOX; EZH2; rev; HECW2; CLK2; NPM1; CPSF3; SYMPK; CSTF2; MDC1; ECT2; BARD1; GTF3C6; FIP1L1; WDR33; POLE3; CPSF1; RALBP1; MED17; GTF3C3; SMARCD3; SMARCA4; POLR2A; CUL3; HNRNPA1; ELAVL1; SUMO2; SMARCAD1; CSTF2T; RRAGA; TBP; PSMA3; CLP1; CDC73; R

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.