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CPSF3 Antibody - N-terminal region : HRP (ARP40840_T100-HRP)

Product Specifications

Gene Name

Cleavage and polyadenylation specific factor 3, 73kDa

Gene Aliases

CPSF73, CPSF-73

Gene ID

51692

Swiss Prot

Q9UKF6

Accession Number

NP_057291

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CPSF3

Target

CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition.

Partner Proteins

UBC; SUMO1; WWOX; AICDA; POLR2A; NPM1; TUT1; SYMPK; CSTF2; CPSF2; PAXIP1; MDC1; BARD1; FIP1L1; POLR1E; WDR33; CPSF1; UBD; SIRT7; SMARCAD1; RRAGA; TBP; CDC73; CLP1; PAPOLA; YWHAG

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

75kDa

References & Citations

Calzado, M.A., (2004) J. Virol. 78 (13), 6846-6854

Shipping Conditions

Wet Ice

Protein Length

684

NCBI Gene Symbol

CPSF3

NCBI GB Accession Number

CPSF3

Host or Source

Rabbit

Protein Name

Cleavage and polyadenylation specificity factor subunit 3

Nucleotide Accession Number

NM_016207

Peptide Sequence

MAAEIPNIKPDILIIESTYGTHIHEKREEREARFCNTVHDIVNRGGRGLI

Subunit

3

Frequently Asked Questions

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