SF3B6 Antibody - middle region: FITC (ARP40829_P050-FITC)
Product Specifications
Gene Name
Splicing factor 3b subunit 6
Gene Aliases
P14, Ht006, SAP14, SAP14a, SF3B14, CGI-110, HSPC175, SF3B14a
Gene ID
51639
Swiss Prot
Q7RTV0
Accession Number
NP_057131
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SF3B14
Target
This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
Partner Proteins
UBC; WWOX; SUZ12; EED; PAN2; ITGA4; FN1; SF3B1; VCAM1; SF3B5; THOC6; WDR18; TRA2A; PRPF19; RBMX; SF3B3; PUF60; DHX15; RCC1; APP; U2AF2; ZNF326; ZC3H18; FTSJ3; PHF5A; TRIM55; SF3B2; UTP14A; USP39; PRPF8; BCAS2; SF3B4; THRAP3; EFTUD2; SRSF11; SART1; VTN; U2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
14kDa
Shipping Conditions
Wet Ice
Protein Length
125
NCBI Gene Symbol
SF3B6
Protein Name
Splicing factor 3B subunit 6
Nucleotide Accession Number
NM_016047
Curated Selection
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