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SF3B6 Antibody - middle region : FITC (ARP40829_P050-FITC)

Selected Variant

ARP40829_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Splicing factor 3b subunit 6

Gene Aliases

P14, Ht006, SAP14, SAP14a, SF3B14, CGI-110, HSPC175, SF3B14a

Gene ID

51639

Swiss Prot

Q7RTV0

Accession Number

NP_057131

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SF3B14

Target

This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

Partner Proteins

UBC; WWOX; SUZ12; EED; PAN2; ITGA4; FN1; SF3B1; VCAM1; SF3B5; THOC6; WDR18; TRA2A; PRPF19; RBMX; SF3B3; PUF60; DHX15; RCC1; APP; U2AF2; ZNF326; ZC3H18; FTSJ3; PHF5A; TRIM55; SF3B2; UTP14A; USP39; PRPF8; BCAS2; SF3B4; THRAP3; EFTUD2; SRSF11; SART1; VTN; U2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

14kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

125

NCBI Gene Symbol

SF3B6

NCBI GB Accession Number

SF3B6

Host or Source

Rabbit

Protein Name

Splicing factor 3B subunit 6

Nucleotide Accession Number

NM_016047

Peptide Sequence

HLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGINTDPPK

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