SF3B6 Antibody - middle region : Biotin (ARP40829_P050-Biotin)

Product Specifications

Gene Name

Splicing factor 3b subunit 6

Gene Aliases

P14, Ht006, SAP14, SAP14a, SF3B14, CGI-110, HSPC175, SF3B14a

Gene ID

51639

Swiss Prot

Q7RTV0

Accession Number

NP_057131

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SF3B14

Target

This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

Partner Proteins

UBC; WWOX; SUZ12; EED; PAN2; ITGA4; FN1; SF3B1; VCAM1; SF3B5; THOC6; WDR18; TRA2A; PRPF19; RBMX; SF3B3; PUF60; DHX15; RCC1; APP; U2AF2; ZNF326; ZC3H18; FTSJ3; PHF5A; TRIM55; SF3B2; UTP14A; USP39; PRPF8; BCAS2; SF3B4; THRAP3; EFTUD2; SRSF11; SART1; VTN; U2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.