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PUM2 Antibody - N-terminal region: Biotin (ARP40810_T100-Biotin)

Product Specifications

Gene Name

Pumilio homolog 2 (Drosophila)

Gene Aliases

PUMH2, PUML2

Gene ID

23369

Swiss Prot

Q8TB72-3

Accession Number

NP_056132

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PUM2

Target

PUM2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.

Partner Proteins

NANOS3; BMI1; gag-pol; UBC; DAZL; DAZ1; ELAVL1; MED4; AURKA; NANOS1; DAZ2; DAZ4; PUM2; MED23; IKZF5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

117kDa

Shipping Conditions

Wet Ice

Protein Length

1064

NCBI Gene Symbol

PUM2

Protein Name

Pumilio homolog 2

Nucleotide Accession Number

NM_015317

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