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EXOSC7 Antibody - N-terminal region : HRP (ARP40797_P050-HRP)

Selected Variant

ARP40797_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Exosome component 7

Gene Aliases

P8, EAP1, RRP42, Rrp42p, hRrp42p

Gene ID

23016

Swiss Prot

B2RDZ9

Accession Number

NP_055819

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC7

Target

EXOSC7 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. The protein is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA.

Partner Proteins

TP53; UBC; RPA3; RPA2; RPA1; rev; HECW2; EXOSC6; EXOSC2; EXOSC10; DXO; AICDA; EXOSC4; APP; DIS3L; EXOSC3; DIS3; EXOSC1; EXOSC5; SKIV2L2; MPP6; EXOSC8; IP6K1; EXOSC9

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

EXOSC7 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

References & Citations

Andersen, J.S., (2005) Nature 433 (7021), 77-83

Shipping Conditions

Wet Ice

Protein Length

291

NCBI Gene Symbol

EXOSC7

NCBI GB Accession Number

EXOSC7

Host or Source

Rabbit

Protein Name

CDNA, FLJ96850 EMBL BAG38096.1

Nucleotide Accession Number

NM_015004

Peptide Sequence

EVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEGYLEFFVDC

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