EXOSC7 Antibody - N-terminal region : Biotin (ARP40797_P050-Biotin)

Product Specifications

Gene Name

Exosome component 7

Gene Aliases

P8, EAP1, RRP42, Rrp42p, hRrp42p

Gene ID

23016

Swiss Prot

B2RDZ9

Accession Number

NP_055819

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC7

Target

EXOSC7 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. The protein is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA.

Partner Proteins

TP53; UBC; RPA3; RPA2; RPA1; rev; HECW2; EXOSC6; EXOSC2; EXOSC10; DXO; AICDA; EXOSC4; APP; DIS3L; EXOSC3; DIS3; EXOSC1; EXOSC5; SKIV2L2; MPP6; EXOSC8; IP6K1; EXOSC9

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

EXOSC7 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.