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EXOSC2 Antibody - N-terminal region : HRP (ARP40762_T100-HRP)

Product Specifications

Gene Name

Exosome component 2

Gene Aliases

P7, RRP4, SHRF, Rrp4p, hRrp4p

Gene ID

23404

Swiss Prot

Q13868

Accession Number

NP_055100

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC2

Target

EXOSC2 belongs to the exosome, a RNA-processing complex, which is at least involved in the 3' processing of the 7S pre-rRNA to the mature 5.8S rRNA. It exhibits a 3'-5' exoribonuclease activity.

Partner Proteins

GPX1; ST6GALNAC1; MRPL48; EXOSC7; RNF8; GALNT13; ZNF408; AICDA; METTL22; UBC; UPF1; MDC1; BARD1; EXOSC5; EXOSC4; EXOSC3; DEK; RAN; EXOSC9; DIS3L; DIS3; UBD; CAND1; HDGF; MEPCE; SKIV2L2; EXOSC6; KHSRP; MPP6; EXOSC8; UPF3A; UPF2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

EXOSC2 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 85%; Horse: 79%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 91%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

References & Citations

Beausoleil, S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135

Shipping Conditions

Wet Ice

Protein Length

293

NCBI Gene Symbol

EXOSC2

NCBI GB Accession Number

EXOSC2

Host or Source

Rabbit

Protein Name

Exosome complex component RRP4

Nucleotide Accession Number

NM_014285

Peptide Sequence

RKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSV

Frequently Asked Questions

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