PUF60 Antibody - C-terminal region : HRP (ARP40760_T100-HRP)

PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

ZG16; ARL8A; LOH12CR1; KIAA1683; MED28; QRICH1; UBE2I; SIAH1; SRSF11; SAP30BP; UPF2; KIAA0907; PUF60; U2AF2; SDCBP; RAD23B; CCNC; SUMO2; SUMO3; CDKN1A; UBC; ERG; EED; H3F3A; FAM129B; VPS29; FAF1; PAPOLA; NUDC; HIRIP3; ZYX; UGP2; TARS; TROVE2; PPM1G; PPP1R

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.