EWSR1 Antibody - middle region : Biotin (ARP40749_P050-Biotin)
Product Specifications
Gene Name
Ewing sarcoma breakpoint region 1
Gene Aliases
EWS, EWS-FLI1, bK984G1.4
Gene ID
2130
Swiss Prot
Q01844
Accession Number
NP_005234
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human EWSR1
Target
EWSR1 is a putative RNA binding protein. Mutations in this gene, specifically a t (11;22) (q24; q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.This gene encodes a putative RNA binding protein. Mutations in this gene, specifically a t (11;22) (q24; q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in two products.
Partner Proteins
SSBP3; SEC24A; TFG; SEC24D; PEF1; MAPK1IP1L; ATPAF2; TRAF2; TRAF1; PLSCR1; PRR13; UBC; RPA3; RPA2; RPA1; EZH2; SUZ12; RNF2; BMI1; rev; ITCH; WBP4; PRMT1; CCDC7; YY1AP1; MRPS18B; UBD; CD81; RIOK2; NONO; ITGB5; ITGA4; FUS; FN1; EWSR1; EPAS1; EP300; HNRNPUL1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Sample Type
EWSR1 is strongly supported by BioGPS gene expression data to be expressed in HeLa EWSR1 is supported by BioGPS gene expression data to be expressed in HEK293
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68kDa
References & Citations
Brandal, P., (2008) Genes Chromosomes Cancer 47 (7), 558-564
Shipping Conditions
Wet Ice
Protein Length
656
NCBI Gene Symbol
EWSR1
NCBI GB Accession Number
EWSR1
Host or Source
Rabbit
Protein Name
RNA-binding protein EWS
Nucleotide Accession Number
NM_005243
Peptide Sequence
QPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQS
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