CPSF1 Antibody - middle region : HRP (ARP40741_P050-HRP)

Product Specifications

Gene Name

Cleavage and polyadenylation specific factor 1, 160kDa

Gene Aliases

MYP27, CPSF160, P/cl.18, HSU37012

Gene ID

29894

Swiss Prot

Q10570

Accession Number

NP_037423

Host

Rabbit

Reactivity

Human, Rat, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CPSF1

Target

CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.

Partner Proteins

REL; RBBP6; UBC; STAU1; LGR4; WWOX; RPA3; RPA2; RPA1; EED; EZH2; NEDD4; TARDBP; ICK; CLK2; HDAC6; NPM1; IL7R; HMOX1; TUT1; FIP1L1; RNPC3; WDR33; CPSF2; MED8; CPSF3; GTF3C3; POLR2A; COPS6; CUL3; SIRT7; SMARCAD1; CSTF2T; PAPOLA; CSTF3; GLIS2; RRAGA; TBP; TA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Horse: 79%; Human: 100%; Rat: 77%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.