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PRPF6 Antibody - C-terminal region: FITC (ARP40734_T100-FITC)

Product Specifications

Gene Name

PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)

Gene Aliases

TOM, ANT1, Prp6, RP60, ANT-1, hPrp6, U5-102K, C20orf14, SNRNP102

Gene ID

24148

Swiss Prot

O94906

Accession Number

NP_036601

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PRPF6

Target

PRPF6 appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. PRPF6 also can bind androgen receptor, providing a link between transcriptional activation and splicing.The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.

Partner Proteins

SUMO2; SUMO3; UBC; MDM2; PASK; RPA3; RPA2; RPA1; EED; rev; PARK2; PRPF4B; UBD; HDAC11; CTNNB1; MMS19; MYC; IK; PRPF31; SRRM2; CD2BP2; WHSC1; NOTCH1; ZNF326; TRA2A; PRPF19; SF3B3; NCSTN; SNRNP200; ACIN1; U2AF2; SUPT16H; PRPF8; RBM14; SAP18; THRAP3; EIF4A3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/mL

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

104kDa

Shipping Conditions

Wet Ice

Protein Length

941

NCBI Gene Symbol

PRPF6

Protein Name

Pre-mRNA-processing factor 6

Nucleotide Accession Number

NM_012469

Curated Selection

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