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XPOT Antibody - middle region : Biotin (ARP40711_P050-Biotin)

Product Specifications

Gene Name

Exportin, tRNA (nuclear export receptor for tRNAs)

Gene Aliases

XPO3

Gene ID

11260

Swiss Prot

O43592

Accession Number

NP_009166

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human XPOT

Target

XPOT belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.

Partner Proteins

SUMO2; SUMO3; UBC; RNF2; MCMBP; PAPSS1; NFRKB; APEX1; FBXO6; EGFR; IQCB1; CA9; ECT2; TXNL1; USP7; UBD; RAN; CUL5; FBXO25; SIRT7; EBNA-LP; HDAC5; MYC; CAMKK2; CLN3; AIRE; XPO7; NUP153; RANBP2; HDLBP; NUP214

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

XPOT is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 75%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

110kDa

References & Citations

Li, S. (2006) RNA Biol 3 (4), 145-149

Shipping Conditions

Wet Ice

Protein Length

962

NCBI Gene Symbol

XPOT

NCBI GB Accession Number

XPOT

Host or Source

Rabbit

Protein Name

Exportin-T

Nucleotide Accession Number

NM_007235

Peptide Sequence

TVLSDQQKANVEAIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLL

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