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IRAK3 Antibody - C-terminal region : FITC (ARP40709_P050-FITC)

Product Specifications

Gene Name

Interleukin-1 receptor-associated kinase 3

Gene Aliases

ASRT5, IRAKM

Gene ID

11213

Swiss Prot

Q9Y616

Accession Number

NP_009130

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human IRAK3

Target

IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.

Partner Proteins

CDCA5; NSA2; LDB1; NTRK3; NONO; HSP90AA1; HOXB7; FOLR1; ECM1; COPB1; CD14; ATP6V0B; ADH1B; IRAK1; UBC; IRAK4; IRAK2; TICAM2; IRAK3; TRAF6; MYD88

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 86%; Rabbit: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

66kDa

References & Citations

Del (2005) J. Immunol. 174 (5), 3032-3040

Shipping Conditions

Wet Ice

Product Datasheet

Anti-IRAK3 (ARP40709_P050-FITC) antibody

Protein Length

596

NCBI Gene Symbol

IRAK3

NCBI GB Accession Number

IRAK3

Host or Source

Rabbit

Protein Name

Interleukin-1 receptor-associated kinase 3

Nucleotide Accession Number

NM_007199

Peptide Sequence

NTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLL

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