CPSF6 Antibody - middle region : HRP (ARP40697_T100-HRP)

Product Specifications

Gene Name

Cleavage and polyadenylation specific factor 6, 68kDa

Gene Aliases

CFIM, CFIM68, CFIM72, HPBRII-4, HPBRII-7

Gene ID

11052

Swiss Prot

Q16630

Accession Number

NP_008938

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CPSF6

Target

CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides.The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitement of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.

Partner Proteins

ARMC7; OTUB2; TOLLIP; PPIL1; FUS; FXR2; WWOX; EZH2; SUZ12; EED; rev; ITCH; PRPF40A; WBP4; TCERG1; NEDD4; APBB1; SRPK2; WWP1; NUDT21; LMNA; CD81; TP63; UBC; NPM1; FN1; DAB2; CSNK2A1; SMURF1; BARD1; MDC1; ZBTB8B; CPSF7; NUP107; TBC1D2; WBP11; PUF60; U2AF2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IF, IHC, WB

Sample Type

CPSF6 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.