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HNRPA0 Antibody - middle region: Biotin (ARP40686_T100-Biotin)

Product Specifications

Gene Name

Heterogeneous nuclear ribonucleoprotein A0

Gene Aliases

HNRPA0

Gene ID

10949

Swiss Prot

Q13151

Accession Number

NP_006796

Host

Rabbit

Reactivity

Human, Cow, Dog, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HNRPA0

Target

HNRPA0 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.

Partner Proteins

UBC; SUMO2; SUMO3; STAU1; RPA3; RPA2; RPA1; EED; RNF2; DYNC1LI1; PSMD13; PSMD12; PSMD8; MAP2; DYNC1I2; DHX9; ABCF1; RPS27; TARDBP; CSF2; NPM1; LMNA; AICDA; MAPKAPK2; GADD45A; U2AF2; VCAM1; SRSF1; NKX3-1; MTNR1A; ITGA4; IL7R; HNRNPK; HNRNPH3; HNRNPH2; HNRN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IF, IP, WB, IHC

Concentration

0.5 mg/mL

Homology

Cow: 93%; Dog: 93%; Human: 100%; Pig: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

34kDa

Shipping Conditions

Wet Ice

Protein Length

305

NCBI Gene Symbol

HNRNPA0

Protein Name

Heterogeneous nuclear ribonucleoprotein A0

Nucleotide Accession Number

NM_006805

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