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SF3A3 Antibody - middle region : FITC (ARP40684_P050-FITC)

Product Specifications

Gene Name

Splicing factor 3a, subunit 3, 60kDa

Gene Aliases

PRP9, PRPF9, SAP61, SF3a60

Gene ID

10946

Swiss Prot

Q12874

Accession Number

NP_006793

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SF3A3

Target

SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.This This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

TRIM69; HUWE1; ZNF212; TADA2A; FUS; UBC; NEDD8; MDM2; WWOX; RNF2; SUZ12; EED; rev; APBB1; ACTN1; ACTN4; STAM2; HGS; SNRPB; CDAN1; PRPF40A; WBP4; TCERG1; UBD; SF3A1; FN1; gag-pol; PRMT5; PRPF19; PRPF31; SF3B1; SF3B3; SF3B4; HNRNPR; DDX46; TOX4; DDX23; PRPF

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SF3A3 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

501

NCBI Gene Symbol

SF3A3

NCBI GB Accession Number

SF3A3

Host or Source

Rabbit

Protein Name

Splicing factor 3A subunit 3

Nucleotide Accession Number

NM_006802

Peptide Sequence

THENVQRKQARTGEEREEEEEEQISESESEDEENEIIYNPKNLPLGWDGK

Subunit

3

Frequently Asked Questions

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