KHDRBS3 Antibody - C-terminal region: FITC (ARP40663_P050-FITC)
Product Specifications
Gene Name
KH domain containing, RNA binding, signal transduction associated 3
Gene Aliases
Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile
Gene ID
10656
Swiss Prot
O75525
Accession Number
NP_006549
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human KHDRBS3
Target
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
Partner Proteins
YTHDC1; DMRT3; MARK4; NCOA5; PRPF31; BAHD1; KHDRBS3; INPP5D; UBC; BMI1; NELFB; RBM7; PSMF1; SIAH1; HNRNPK; KHDRBS2; CCDC33; PTBP2; U2AF2; KHDRBS1; SNRPC; HNRNPC; FUS; FBXO32; SERPINB5; RBBP6; CACNA1A; RPAP2; ZNF408; LNX1; SGSM2; SRSF9; NUDT18; PRMT1; RBMY
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
38kDa
Shipping Conditions
Wet Ice
Protein Length
346
NCBI Gene Symbol
KHDRBS3
Protein Name
KH domain-containing, RNA-binding, signal transduction-associated protein 3
Nucleotide Accession Number
NM_006558
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