KHDRBS3 Antibody - C-terminal region : FITC (ARP40663_P050-FITC)

Product Specifications

Gene Name

KH domain containing, RNA binding, signal transduction associated 3

Gene Aliases

Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile

Gene ID

10656

Swiss Prot

O75525

Accession Number

NP_006549

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KHDRBS3

Target

As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.

Partner Proteins

YTHDC1; DMRT3; MARK4; NCOA5; PRPF31; BAHD1; KHDRBS3; INPP5D; UBC; BMI1; NELFB; RBM7; PSMF1; SIAH1; HNRNPK; KHDRBS2; CCDC33; PTBP2; U2AF2; KHDRBS1; SNRPC; HNRNPC; FUS; FBXO32; SERPINB5; RBBP6; CACNA1A; RPAP2; ZNF408; LNX1; SGSM2; SRSF9; NUDT18; PRMT1; RBMY

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.