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PPIE Antibody - middle region: FITC (ARP40627_T100-FITC)

Product Specifications

Gene Name

Peptidylprolyl isomerase E (cyclophilin E)

Gene Aliases

CYP33, CYP-33

Gene ID

10450

Swiss Prot

Q9UNP9

Accession Number

NP_006103

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PPIE

Target

PPIE is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Partner Proteins

XAB2; BMI1; UBC; EIF4A3; MAGOH; SF3A2; HHV8GK18_gp81; SUMO2; Prpf8; Cdc5l; Snw1; KMT2A; PHYHIP

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

PPIE is strongly supported by BioGPS gene expression data to be expressed in K562

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%; Sheep: 100%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

Shipping Conditions

Wet Ice

Protein Length

301

NCBI Gene Symbol

PPIE

Protein Name

Peptidyl-prolyl cis-trans isomerase E

Nucleotide Accession Number

NM_006112

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