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SNUPN Antibody - middle region : HRP (ARP40598_P050-HRP)

Selected Variant

ARP40598_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Snurportin 1

Gene Aliases

KPNBL, RNUT1, Snurportin1

Gene ID

10073

Swiss Prot

O95149

Accession Number

NP_005692

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SNUPN

Target

The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Partner Proteins

UBC; HOTAIR; MEX3B; XPO1; GCNT3; RNF126; DBN1; RPL17; KPNB1; PAFAH1B2; TNNT3; PEX5; ENO2; RAN; DDX20; ZPR1; SNRPB; SMN1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

References & Citations

Ospina, J.K., (2005) Mol. Biol. Cell 16 (10), 4660-4671

Shipping Conditions

Wet Ice

Protein Length

360

NCBI Gene Symbol

SNUPN

NCBI GB Accession Number

SNUPN

Host or Source

Rabbit

Protein Name

Snurportin-1

Nucleotide Accession Number

NM_005701

Peptide Sequence

GVAVPAGPLTTKPDYAGHQLQQIMEHKKSQKEGMKEKLTHKASENGHYEL

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