SNUPN Antibody - middle region : FITC (ARP40598_P050-FITC)
Product Specifications
Gene Name
Snurportin 1
Gene Aliases
KPNBL, RNUT1, Snurportin1
Gene ID
10073
Swiss Prot
O95149
Accession Number
NP_005692
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SNUPN
Target
The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Partner Proteins
UBC; HOTAIR; MEX3B; XPO1; GCNT3; RNF126; DBN1; RPL17; KPNB1; PAFAH1B2; TNNT3; PEX5; ENO2; RAN; DDX20; ZPR1; SNRPB; SMN1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 85%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
41kDa
References & Citations
Ospina, J.K., (2005) Mol. Biol. Cell 16 (10), 4660-4671
Shipping Conditions
Wet Ice
Protein Length
360
NCBI Gene Symbol
SNUPN
NCBI GB Accession Number
SNUPN
Host or Source
Rabbit
Protein Name
Snurportin-1
Nucleotide Accession Number
NM_005701
Peptide Sequence
GVAVPAGPLTTKPDYAGHQLQQIMEHKKSQKEGMKEKLTHKASENGHYEL
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