What sizes are available for KARS Antibody - C-terminal region : Biotin (ARP40589_P050-Biotin)?

KARS Antibody - C-terminal region : Biotin (ARP40589_P050-Biotin) is available in the following size(s): 100 µL.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

KARS Antibody - C-terminal region : Biotin (ARP40589_P050-Biotin)

Q: What is the catalog number for KARS Antibody - C-terminal region : Biotin (ARP40589_P050-Biotin)?

The catalog number for KARS Antibody - C-terminal region : Biotin (ARP40589_P050-Biotin) is ARP40589_P050-Biotin.

Selected Variant

ARP40589_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Lysyl-tRNA synthetase

Gene Aliases

KRS, KARS, KARS2, LEPID, CMTRIB, DEAPLE, DFNB89

Gene ID

3735

Swiss Prot

Q15046

Accession Number

NP_005539

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KARS

Target

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.

Partner Proteins

AIMP2; SUMO2; SUMO3; MDM2; UBC; SUMO1; NEDD8; STAT1; SSB; RPL21; RPL19; RPL17; NAP1L4; HSPA4; GPX1; CARS; APEH; CAND1; RANBP6; RPL36; JMJD6; NUDC; IPO7; AIMP1; SH3RF2; FBXO6; vpr; MSK1; gag; FN1; TRMT1; MRPS18B; UBE2S; CCT8; EEF1E1; VBP1; UBA1; RARS; QARS

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

KARS is strongly supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 92%; Guinea Pig: 85%; Horse: 88%; Human: 100%; Mouse: 79%; Pig: 86%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

66kDa

References & Citations

Halwani, R., (2004) J. Virol. 78 (14), 7553-7564

Shipping Conditions

Wet Ice

Protein Length

597

NCBI Gene Symbol

KARS

NCBI GB Accession Number

KARS

Host or Source

Rabbit

Protein Name

Lysine--tRNA ligase

Nucleotide Accession Number

NM_005548

Peptide Sequence

GMGIDRVAMFLTDSNNIKEVLLFPAMKPEDKKENVATTDTLESTTVGTSV

Price

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