HNRNPDL Antibody - C-terminal region : Biotin (ARP40586_P050-Biotin)

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.

SPRTN; SUMO2; SUMO3; UBC; RPA3; RPA2; RPA1; ERG; EED; RNF2; rev; PARK2; FBXO6; TARDBP; HMGA1; ITGA4; IL7R; IFIT3; IFIT2; FN1; CSNK2A1; BARD1; EEF2; EEF1A1; DDX3X; ATP6V1B1; HNRNPA3; WIPF2; RMDN3; MRPS16; UBE2S; LSM14A; RPL36; U2AF2; HNRNPUL1; HNRNPA0; HNR

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.