NCL Antibody - C-terminal region : Biotin (ARP40584_T100-Biotin)
Product Specifications
Gene Name
Nucleolin
Gene Aliases
C23, Nsr1
Gene ID
4691
Swiss Prot
P19338
Accession Number
NP_005372
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human NCL
Target
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus.Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
Partner Proteins
HUWE1; PIK3R1; PA2G4; NCL; HNRNPD; AURKA; MDM2; NFE4; CDKN1A; ADAP1; STAU1; ADAP2; UBC; NUP62; ZBTB1; ARFGEF1; RPA3; RPA2; RPA1; ERG; RNF2; SUZ12; EED; EZH2; BMI1; NPM3; EIF3G; XRCC5; PLOD2; NCBP1; MCM2; LMNA; PRMT1; HNRNPK; KCTD12; DNM1; ACLY; SRPK3; TAR
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
NCL is supported by BioGPS gene expression data to be expressed in Daudi
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
78kDa
References & Citations
Huang, Y., (2006) Blood 107 (9), 3564-3571
Shipping Conditions
Wet Ice
Protein Length
710
NCBI Gene Symbol
NCL
NCBI GB Accession Number
NCL
Host or Source
Rabbit
Protein Name
Nucleolin
Nucleotide Accession Number
NM_005381
Peptide Sequence
GGFGGRGGGRGGRGGFGGRGRGGFGGRGGFRGGRGGGGDHKPQGKKTKFE
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