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ZRSR2 Antibody - C-terminal region : HRP (ARP40573_T100-HRP)

Selected Variant

ARP40573_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

Gene Aliases

URP, ZC3H22, U2AF1L2, U2AF1RS2, U2AF1-RS2

Gene ID

8233

Swiss Prot

Q15696

Accession Number

NP_005080

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ZRSR2

Target

ZRSR2 is an essential splicing factor. The protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly.This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with the U2AF heterodimer composed of a large and a small subunit. It specifically interacts with the large subunit through an U2AF small subunit homologous region, and with SR proteins through its RS domain. This protein and U2AF small subunit are not functionally redundant.

Partner Proteins

CLK2; SSX2IP; SDCBP2; SRPK2; UBC; SRPK1; APP; SRSF2; SRSF1; U2AF2; U2AF1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 92%; Guinea Pig: 100%; Horse: 79%; Human: 100%; Mouse: 90%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53kDa

References & Citations

Will, C.L., (2004) RNA 10 (6), 929-941

Shipping Conditions

Wet Ice

Protein Length

482

NCBI Gene Symbol

ZRSR2

NCBI GB Accession Number

ZRSR2

Host or Source

Rabbit

Protein Name

U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

Nucleotide Accession Number

NM_005089

Peptide Sequence

HHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERH

Subunit

-related protein 2

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