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EIF4G1 Antibody - middle region : Biotin (ARP40562_P050-Biotin)

Selected Variant

ARP40562_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Eukaryotic translation initiation factor 4 gamma, 1

Gene Aliases

P220, EIF4F, EIF4G, EIF4GI, PARK18, EIF-4G1

Gene ID

1981

Swiss Prot

Q04637

Accession Number

NP_886553

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human EIF4G1

Target

EIF4G1 is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome.The protein encoded by this gene is a component of the protein complex EIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure, and recruitment of mRNA to the ribosome. Alternative splicing results in five transcript variants encoding four distinct isoforms.

Partner Proteins

POLDIP3; EIF4E; UBC; NCBP1; SUMO1; SUMO2; MDM2; LGR4; AIMP1; IQGAP1; EEF1E1; AIMP2; QARS; PTBP1; PSMB8; TARDBP; UBD; BRCA1; ITGA4; GK; FN1; HTRA2; ZFYVE9; VCAM1; HNRNPD; ESR1; EIF4G3; FTL; EIF4G2; RAB31; SF3A3; EIF4B; EIF4A1; TRAF2; CUL3; ISG15; YWHAZ; SI

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

EIF4G1 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 79%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

175kDa

References & Citations

Petersen, K.E., (2008) J. Cell Biol. 181 (2), 293-307

Shipping Conditions

Wet Ice

Protein Length

1599

NCBI Gene Symbol

EIF4G1

NCBI GB Accession Number

EIF4G1

Host or Source

Rabbit

Protein Name

Eukaryotic translation initiation factor 4 gamma 1

Nucleotide Accession Number

NM_182917

Peptide Sequence

PAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQ

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