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FXR2 Antibody - middle region : Biotin (ARP40557_P050-Biotin)

Product Specifications

Gene Name

Fragile X mental retardation, autosomal homolog 2

Gene Aliases

FXR2P, FMR1L2

Gene ID

9513

Swiss Prot

P51116

Accession Number

NP_004851

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human FXR2

Target

FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

MORF4L1; FMR1; MRPL43; PRAM1; CEP44; HMBOX1; C1orf35; NIF3L1; TBC1D22B; CEP55; FAM90A1; PAF1; LASP1; POM121; FXR2; ZBTB22; AP1M1; SCEL; YES1; SRPK2; PIM1; PCBD1; MFAP1; LCP2; CDKL3; BAZ2B; CAMK2D; BYSL; C10orf62; MIA3; ZMAT2; SYT6; SYTL4; NDN; KIF1A; UBC

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

FXR2 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

74kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

673

NCBI Gene Symbol

FXR2

NCBI GB Accession Number

FXR2

Host or Source

Rabbit

Protein Name

Fragile X mental retardation syndrome-related protein 2

Nucleotide Accession Number

NM_004860

Peptide Sequence

RGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDPPTRGEESRRR

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