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EIF4E2 Antibody - N-terminal region : HRP (ARP40555_T100-HRP)

Product Specifications

Gene Name

Eukaryotic translation initiation factor 4E family member 2

Gene Aliases

4EHP, IF4e, 4E-LP, h4EHP, EIF4EL3

Gene ID

9470

Swiss Prot

O60573

Accession Number

NP_004837

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human EIF4E2

Target

EIF4E2 belongs to the eukaryotic initiation factor 4E family. It recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Partner Proteins

USHBP1; CARD9; PRDM14; HOMEZ; TRIM54; NECAB2; ADAMTSL4; AMOTL2; SPAG5; SPRY2; HUWE1; TMCC2; MAGED1; TCF4; TADA2A; TRIM27; REL; MYOG; KRT31; KRT19; KRT13; CDR2; AES; MAPRE3; NOTCH2NL; KRTAP10-8; KRTAP10-5; KRTAP10-9; ZBTB9; SPERT; USP54; MIPOL1; KRT40; UBX

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

There is BioGPS gene expression data showing that EIF4E2 is expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 79%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

References & Citations

Tee, A.R., FEBS Lett. 564 (1-2), 58-62 (2004)

Shipping Conditions

Wet Ice

Protein Length

245

NCBI Gene Symbol

EIF4E2

NCBI GB Accession Number

EIF4E2

Host or Source

Rabbit

Protein Name

Eukaryotic translation initiation factor 4E type 2

Nucleotide Accession Number

NM_004846

Peptide Sequence

KDDDSGDHDQNEENSTQKDGEKEKTERDKNQSSSKRKAVVPGPAEHPLQY

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